| Deals Gap, North Carolina | 606 m | | Western Great Smoky Mountains |
| Chilly Spring Gap | 601 m | | Western Great Smoky Mountains |
| Schoolhouse Gap | 600 m | | Western Great Smoky Mountains |
| Whistling Gap | 599 m | | Western Great Smoky Mountains |
| Shaw Grave Gap | 576 m | | Western Great Smoky Mountains |
| Headrick Gap | 561 m | | Western Great Smoky Mountains |
| Wear Cove Gap | 557 m | | Central Great Smoky Mountains |
| Dosey Gap | 550 m | | Western Great Smoky Mountains |
| Emerine Gap | 538 m | | Western Great Smoky Mountains |
| Tarkiln Gap | 503 m | | Western Great Smoky Mountains |
| Cumberland Gap | 497 m | | Cumberland-Stone Mountain |
| Huckleberry Gap | 422 m | | Western Great Smoky Mountains |
| Happy Valley Gap | 399 m | | Western Great Smoky Mountains |
| Abrams Gap | 365 m | | Western Great Smoky Mountains |
| Chilogatee Gap | 228 m | | Western Great Smoky Mountains |
| William Bean Gap | | | Clinch Mountain Complex |
| Wilson Gap | | | Cumberland-Stone Mountain |
| Tate Gap | | | Unicoi Mountains |
| Blackgum Gap | | | Eastern Great Smoky Mountains |
| Vaught Gap | | | Beech-Snake-Rich |