| Laurel Fork Gap | 636 m | | South North Carolina Blue Ridge Crest |
| Salt Rock Gap | | | South North Carolina Blue Ridge Crest |
| Red Ridge Gap | 1114 m | | Western Great Smoky Mountains |
| Jakes Gap | 1237 m | | Central Great Smoky Mountains |
| Deep Creek Gap | 1009 m | | Central Great Smoky Mountains |
| Mack Gap | 852 m | | Cowee Mountains |
| Collins Gap | 1745 m | | Central Great Smoky Mountains |
| Reed's Gap | | | South Central Virginia Blue Ridge |
| Lick Log Gap | 1039 m | | North North Carolina Blue Ridge Crest |
| Dry Sluice Gap | 1579 m | | Eastern Great Smoky Mountains |
| Scott Gap | 621 m | | Western Great Smoky Mountains |
| Cherry Gap | 1094 m | | Central Great Smoky Mountains |
| Proctor Field Gap | 720 m | | Western Great Smoky Mountains |
| Dickey Gap | 1003 m | | Iron Mountains-Mount Rogers |
| The Narrows | 1628 m | | Central Great Smoky Mountains |
| Sweetwater Gap | 981 m | | Cheoah Mountains |
| Tate Gap | | | Unicoi Mountains |
| Mease Gap | | | Great Balsam Mountains |
| Locust Gap | 1123 m | | Central Great Smoky Mountains |
| Panther Gap | | | Nantahala Mountains |