| Big Abrams Gap | 1244 m | | Western Great Smoky Mountains |
| Low Gap | 542 m | | Shenandoah-North Section |
| Squirrel Gap | | | Newfound Mountain Region |
| Jenks Gap | | | Unicoi Mountains |
| Swinging Lick Gap | 1250 m | | Nantahala Mountains |
| Cherry Log Gap | | | Unicoi Mountains |
| State Line Gap | 1142 m | | Beech-Snake-Rich |
| Little Creek Gap | | | Newfound Mountain Region |
| Low Gap | | | Bald Mountains |
| Yellow Mountain Gap | | | Roan-Unaka Mountains |
| Slicking Gap | 875 m | | South North Carolina Blue Ridge Crest |
| Carringer Gap | 258 m | | Cheoah Mountains |
| Gravel Springs Gap | 813 m | | Shenandoah-North Section |
| Loggy Gap | 1086 m | | Beech-Snake-Rich |
| Murray Gap | 708 m | | Western Great Smoky Mountains |
| Indian Grave Gap | | | Roan-Unaka Mountains |
| Coldspring Gap | | | Unicoi Mountains |
| Turkey Cove Gap | 879 m | | Western Great Smoky Mountains |
| Board Camp Gap | 1197 m | | Central Great Smoky Mountains |
| Wilkerson Gap | 781 m | | Peaks of Otter-Apple Orchard Area |