| Sugartree Gap | 1363 m | | Central Great Smoky Mountains |
| Turkey Gap | | | Newfound Mountain Region |
| Bradley Gap | 1516 m | | Roan-Unaka Mountains |
| Sandy Gap | 1005 m | | North North Carolina Blue Ridge Crest |
| Chinquapin Gap | | | South North Carolina Blue Ridge Crest |
| Deep Gap | 1323 m | | Nantahala Mountains |
| Brown Gap | 1067 m | | Newfound Mountain Region |
| Gillespie Gap | 855 m | | North North Carolina Blue Ridge Crest |
| Beasley Gap | 575 m | | South North Carolina Blue Ridge Crest |
| Harrison Gap | | | Unicoi Mountains |
| Tipton Gap | | | Unicoi Mountains |
| Alum Gap | 1742 m | | Eastern Great Smoky Mountains |
| Hurricane Gap | 900 m | | Bald Mountains |
| Alder Gap | 930 m | | North North Carolina Blue Ridge Crest |
| Cowee Gap | 1280 m | | South North Carolina Blue Ridge Crest |
| Cowcamp Gap | 1059 m | | South Central Virginia Blue Ridge |
| Upper Gap | 626 m | | South North Carolina Blue Ridge Crest |
| Billy Cove Gap | | | Great Balsam Mountains |
| Shaw Grave Gap | 576 m | | Western Great Smoky Mountains |
| Cold Mountain Gap | | | South North Carolina Blue Ridge Crest |