| Jarman Gap | 662 m | | Shenandoah-South Section |
| Little Brier Gap | 662 m | | Central Great Smoky Mountains |
| Deals Gap, North Carolina | 663 m | | Western Great Smoky Mountains |
| Trammel Gap | 670 m | | South North Carolina Blue Ridge Crest |
| Allen Gap | 681 m | | Bald Mountains |
| Flint Gap | 685 m | | Western Great Smoky Mountains |
| Bearwallow Gap | 688 m | | Peaks of Otter-Apple Orchard Area |
| Lone Pine Gap | 689 m | | Bald Mountains |
| Tanyard Gap | 694 m | | Bald Mountains |
| Fighting Creek Gap | 698 m | | Central Great Smoky Mountains |
| Powell Gap | 699 m | | Shenandoah-South Section |
| Bearpen Gap | 700 m | | Western Great Smoky Mountains |
| Humphreys Gap | 706 m | | South Central Virginia Blue Ridge |
| Murray Gap | 708 m | | Western Great Smoky Mountains |
| Gragg Gap | 710 m | | Newfound Mountain Region |
| Buckhorn Gap | 714 m | | Central Great Smoky Mountains |
| Caylor Gap | 715 m | | Western Great Smoky Mountains |
| Dills Gap | 716 m | | Cowee Mountains |
| Proctor Field Gap | 720 m | | Western Great Smoky Mountains |
| Augerhole Gap | 720 m | | Western Great Smoky Mountains |